Nursing Careers

​​​​​​​A place where nurses thrive

At Prisma Health, each of our nurses brings their own unique characteristics to their jobs. But what binds us together is our common commitment to Inspire health. Serve with compassion. Be the difference.​​​​​

RN sign-on bonus currently available

Now is the perfect time to join Prisma Health if you are an experienced RN with a minimum of 1-year of Registered Nurse experience and licensed in South Carolina! We offer up to a $25,000 sign-on bonus for eligible full-time positions. Prisma Health requires a 12 month commitment (we're confident you're going to love working here). We also offer $5,250 Student Tax-free Loan Repayment (per year) and relocation assistance!
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"From New Grads to Nurse Managers, each nursing teammate contributes their unique experience and distinct passion to our hospitals, patients, and each other. Now, more than ever, Prisma Health is committed to our nurses. With educational assistance, generous sign-on bonuses, and flexible schedule options, Prisma Health is truly a place where nurses thrive. It is of vital importance that our nurses feel encouraged and supported by us every step of their career journey."

Jean Meyer, MSN, RN

SVP - Acute Care Operations and Chief Nursing Officer​​​​​​​

"Nursing is my calling, and I am forever grateful for the opportunity I have at Prisma Health to make a positive impact on others”

"My nursing skills are being nurtured and further developed in an environment where teamwork is important and success is a common goal.”

"Being a nurse at Prisma Health is great because of the many opportunities for leadership development. Since coming to Prisma Health, I have been mentored by those in leadership roles; and as I have learned the essential components of leadership, I have been granted additional opportunity and responsibility within the hospital.”

"Being a nurse at Prisma Health is great because I love having the opportunity to provide bedside care and work closely with our interdisciplinary team to ensure excellent care for our patients.”
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Professional Practice Models (PPM)

Prisma Health Nursing practice is guided by Professional Practice Models (PPM) that depict how nurses practice, collaborate, communicate and develop professionally. These models are designed to support their control over the delivery of nursing care and the environment in which that care is delivered and are centered on the caring relationship between nurses and patients.

Nursing Per Diem Program


We are excited to introduce a new Per Diem Program that allows for flexible scheduling opportunities for Acute Care Nurses. Over the past several months, we have recognized that a one-size-fits-all model for PRN nurses is not effective at attracting or retaining these valuable team members. Our new program offers a five-tier per diem (PRN) campus-based program that offers flexibility in addressing staffing needs:

  • Tier 1 is unit-based assignment and standard PRN commitment*
  • Tier 2 requires 2 years of experience and is a unit-based assignment where a team member may work like-units or competency-based assignments with a minimum 48-hour commitment for a 6-week period*
  • Tier 3 requires 2 years of experience and is a unit-based assignment where a team member may work like-units or competency-based assignments with a minimum 96-hour commitment for a 6-week period *
  • Tier 4 is an Internal Resource Pool (IRP) assignment where a team member works like units or competency-based assignments with a minimum 96-hour commitment for a 6-week period in addition to commitment to cover three (3) designated hospitals *
  • Tier 5 is an Internal Resource Pool (IRP) assignment where a team member works a full-time (minimum 36 hours per week) commitment for a 12-week period with agreement to travel across system hospitals to “like” units or competency-based assignments.

*Commitment to holiday/weekends shifts; please refer to the per diem grid.