Nursing Careers

​​​​​​​A place where nurses thrive

At Prisma Health, each of our nurses brings their own unique characteristics to their jobs. But what binds us together is our common commitment to Inspire health. Serve with compassion. Be the difference.​​​​​

RN sign-on bonus currently available

Now is the perfect time to join Prisma Health if you are an experienced RN with a minimum of 1-year of Registered Nurse experience and licensed in South Carolina! We offer several sign-on bonuses for eligible full-time positions. Prisma Health requires a 12 month commitment (we're confident you're going to love working here). We also offer $5,250 Student Tax-free Loan Repayment (per year) and relocation assistance!
"Nursing is my calling, and I am forever grateful for the opportunity I have at Prisma Health to make a positive impact on others”

"My nursing skills are being nurtured and further developed in an environment where teamwork is important and success is a common goal.”

"Being a nurse at Prisma Health is great because of the many opportunities for leadership development. Since coming to Prisma Health, I have been mentored by those in leadership roles; and as I have learned the essential components of leadership, I have been granted additional opportunity and responsibility within the hospital.”

"Being a nurse at Prisma Health is great because I love having the opportunity to provide bedside care and work closely with our interdisciplinary team to ensure excellent care for our patients.”
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Professional Practice Models (PPM)

Prisma Health Nursing practice is guided by Professional Practice Models (PPM) that depict how nurses practice, collaborate, communicate and develop professionally. These models are designed to support their control over the delivery of nursing care and the environment in which that care is delivered and are centered on the caring relationship between nurses and patients.

Nursing Per Diem Program


We are excited to introduce a new Per Diem Program that allows for flexible scheduling opportunities for Acute Care Nurses. Over the past several months, we have recognized that a one-size-fits-all model for PRN nurses is not effective at attracting or retaining these valuable team members. Our new program offers a five-tier per diem (PRN) campus-based program that offers flexibility in addressing staffing needs:

  • Tier 1 is a campus unit-based assignment with the standard PRN commitment of 24 hours over a 6 week period, weekend commitment based on unit needs and 1 holiday per year.
  • Tier 2 is a campus unit-based assignment, where a team member may work like-units or competency-based assignments with a minimum 48 hour commitment over a 6-week schedule, including 2 weekend shifts and 1 holiday per year.
  • Tier 3 is a campus unit-based assignment, where a team member may work like-units or competency-based assignments with a minimum 96 hour commitment for a 6-week schedule, including 3 weekend shifts and 2 holidays per year.
  • Tier 4 is in the Internal Resource Pool (IRP), where a team member receives daily assignment to units within their competency-based skill set and must float to all campuses in either the Upstate or Midlands market. This positions requires a minimum 108 hour commitment over a 6 week schedule, including 3 weekend shifts and 2 holidays per year.
  • Tier 5 is a part-time position in the Internal Resource Pool (IRP), where a team member receives daily assignment to units within their competency-based skill set and must float to all campuses in either the Upstate or Midlands market. This position requires a commitment of 24 hours per week, 3 weekend shifts over a 6 week schedule and 2 holidays per year.
  • Tier 6 is a full-time position in the Internal Resource Pool (IRP), where a team member receives daily assignment to units within their competency-based skill set and must float to all campuses in either the Upstate or Midlands market. This position requires a commitment of 36 hours per week, 6 weekend shifts over a 6 week schedule and 4 holidays per year.
  • Tier 7 is a full-time Internal Traveler position in the Internal Resource Pool (IRP), where a team member works a 12 week assignment in a specific unit/hospital within their competency-based skillset. New 12 week assignments will be on a different unit and is based on highest vacancy. This position requires a commitment of 36 hours per week, 6 weekend shifts over a 6 week schedule and 4 holidays per year.

*For additional information; please refer to the per diem grid.