Prisma Health is committed to giving new graduate nurses a strong start to their careers. Our 12-month Nurse Residency Program (NRP), offered in our South Carolina markets (Tennessee Nurse Residency Program launches in 2026), provides a supportive bridge from student to professional nurse, offering:
High-quality classes and simulation training.
One-on-one skills validation and hands-on practice with preceptors.
Ongoing professional development.
Networking opportunities with fellow graduates.
Exposure to diverse nursing roles across the Prisma Health hospitals in South Carolina.
Weeks 2 to 9: Residents work 2 to 3 shifts per week on their assigned unit with a dedicated preceptor. This is combined with specialty-specific classes that cover essential topics such as healthcare foundations, behavioral health, crucial conversations, emergency response, stroke care, respiratory care, and other skill competencies specific to the clinical setting.
Weeks 10 to 52: Completion of unit orientation and transition to practice, followed by ongoing quarterly professional development training and skill refreshers to support your growth and confidence throughout your first year.
How to Apply
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Program Requirements
Education: Graduate from an accredited nursing program (ADN/ASN, BSN, MSN, or LPN).
Experience: Have less than 12 months of paid work experience as an RN or LPN.
Licensure: Must have a current South Carolina or Compact State RN/LPN license, issued no later than the Wednesday before the program start date.
Start date eligibility: Apply to a cohort that begins at least 45 days after the expected graduation date from a nursing program.
Application Process
Browse opportunities: View current nurse residency openings here.
Choose your units: Our program is not rotational. Nurse residents are hired directly into a specific unit. We recommend applying to multiple areas of interest, as availability may vary in each cohort.
Submit your application: Complete an application for each preferred unit and attach your current resume and one clinical letter of recommendation to each application.
Secure your spot: Due to high demand, some units may close applications early. If your preferred unit is not available, we encourage you to explore other available units.
Now accepting applications for December 2025
New graduate nurses who graduated before October 2025 or prior with less than 1 year of RN/LPN work experience.
New graduate nurses who graduate prior to January 2026 with less than 1 year of RN/LPN work experience.
Applications open on 10/03/2025.
Interviews and offers will occur between October and January.
Nurse Residency Service Lines
Residency positions are available based on unit staffing needs. As a result, not all units or service lines accept nurse residents in every cohort. Available units and service lines will be posted on the career website once applications open for each cohort.
We want to support you as you grow and develop in your nursing career. We understand that pursuing a higher education can be challenging and costly. That's why we have partnered with Bright Horizons EdAssist Solutions to offer a tuition assistance program designed to help ease the financial burden.
We want to make interviews with our team as easy and accessible as possible. If you are selected for an interview and would like to meet with us in person, contact your Nurse Residency Recruiter. We can arrange travel accommodations or reimburse mileage for your trip to the interview.
Sign-On Bonus
We are excited to offer a $5,000 taxable sign-on bonus for select service lines. Visit our sign-on bonus page to view current eligible opportunities. This bonus is also available to internal hires joining the Nurse Residency Program.
We are committed to supporting students in every way possible. We currently offer up to $5,250 in tax-free annual student loan repayment support for both full-time and part-time team members.
Have questions about the Nurse Residency program? Join our monthly virtual Q&A for a one-on-one chat with a recruiter to learn more about program details, application tips, and how to launch your nursing career at Prisma Health.
Student Nursing ProgramsAre you a student nurse looking to gain valuable clinical experience? Explore our Nursing Academics page for opportunities that help you build skills, learn from experienced nurses, and jumpstart your career with Prisma Health.
